AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

DNA MAKES RNA MAKES PROTEIN

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What type of mutation results when a single nucleotide is exchanged for a different nucleotide?
A
deletion
B
addition
C
substitution
D
translocation
Explanation: 

Detailed explanation-1: -Base substitutions are the simplest type of gene-level mutation, and they involve the swapping of one nucleotide for another during DNA replication.

Detailed explanation-2: -A nucleotide substitution results in a stop codon and consequently premature truncation of the protein. This protein is generally non-functional. This is known as a stop gain change or a nonsense variant (mutation).

Detailed explanation-3: -Substitution mutations are a type of mutation in which a single nucleotide is substituted with a different nucleotide. Examples of (base-pair) substitutions: a purine is substituted with a different purine (A

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