AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

DNA MAKES RNA MAKES PROTEIN

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
When substitution of bases do not change the protein structure (amino acid) this type of mutation is known as ____
A
Point Mutation-Substitution
B
Frameshift Mutation-Insertion
C
Point Mutation-Silent
D
Frameshift Mutation-Deletion
Explanation: 

Detailed explanation-1: -Silent mutations are base substitutions that result in no change of the amino acid or amino acid functionality when the altered messenger RNA (mRNA) is translated. For example, if the codon AAA is altered to become AAG, the same amino acid – lysine – will be incorporated into the peptide chain.

Detailed explanation-2: -Silent mutations are mutations, or changes, to a gene’s DNA sequence that have no effect on the amino acid sequence coded for by that gene; they are called silent because their effect cannot be heard.

Detailed explanation-3: -The type of base substitution mutation through which the amino acid encoded by the mutated codon of mRNA does not change. These mutations occur at the third position of the codon.

Detailed explanation-4: -Point mutations that alter the resulting protein sequences are called nonsynonymous mutations, while those that do not alter protein sequences are called silent or synonymous mutations.

Detailed explanation-5: -Silent mutation: Silent mutations cause a change in the sequence of bases in a DNA molecule, but do not result in a change in the amino acid sequence of a protein (Figure 1).

There is 1 question to complete.