AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

DNA MAKES RNA MAKES PROTEIN

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which enzyme is responsible for unwinding and unzipping DNA for replication?
A
DNA helicase
B
DNA ligase
C
DNA polymerase III
D
RNA primase
Explanation: 

Detailed explanation-1: -Helicases are enzymes that use ATP-driven motor force to unwind double-stranded DNA or RNA. Recently, increasing evidence demonstrates that some helicases also possess rewinding activity-in other words, they can anneal two complementary single-stranded nucleic acids.

Detailed explanation-2: -Key enzyme involved in DNA replication, it is responsible for ‘unzipping’ the double helix structure by breaking the hydrogen bonds between bases on opposite strands of the DNA molecule.

Detailed explanation-3: -Helicases are enzymes that bind and may even remodel nucleic acid or nucleic acid protein complexes. There are DNA and RNA helicases. DNA helicases are essential during DNA replication because they separate double-stranded DNA into single strands allowing each strand to be copied.

Detailed explanation-4: -Helicases are involved in virtually all cellular processes that involve DNA and RNA. Their claim to fame, though, is unwinding DNA so it can be copied during cell division.

Detailed explanation-5: -DNA helicases catalyze the disruption of the hydrogen bonds that hold the two strands of double-stranded DNA together. This energy-requiring unwinding reaction results in the formation of the single-stranded DNA required as a template or reaction intermediate in DNA replication, repair and recombination.

There is 1 question to complete.