AP BIOLOGY

Detailed explanation-1: -Such a substitution could: change a codon to one that encodes a different amino acid and cause a small change in the protein produced. For example, sickle cell anemia is caused by a substitution in the beta-hemoglobin gene, which alters a single amino acid in the protein produced.

Detailed explanation-2: -These hereditary (or inherited) mutations are in almost every cell of the person’s body throughout their life. Hereditary mutations include cystic fibrosis, hemophilia, and sickle cell disease.

Detailed explanation-3: -Substitution mutations can be good, bad, or have no effect. They cause three specific types of point mutation: silent, missense, and nonsense mutations. A silent mutation is one where the function of the protein is not changed. A missense mutation codes for the wrong protein.