AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

DNA MAKES RNA MAKES PROTEIN

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which mutation in DNA affects only one nucleotide in a sequence?
A
inversion
B
frameshift
C
addition
D
substituion
Explanation: 

Detailed explanation-1: -With base substitution mutations, only a single nucleotide within a gene sequence is changed, so only one codon is affected (Figure 1).

Detailed explanation-2: -Substitutions result in a change that only affect one codon. This is known as a point mutation.

Detailed explanation-3: -Substitution Substitution, as related to genomics, is a type of mutation in which one nucleotide is replaced by a different nucleotide. The term can also refer to the replacement of one amino acid in a protein with a different amino acid.

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