THE MOLECULAR BASIS OF INHERITANCE
DNA MAKES RNA MAKES PROTEIN
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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The deletion of a single adenine nucleotide in the middle of a gene.
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The addition of the nucleotides that make up an additional stop codon to the end of a gene.
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The substitution of a thymine nucleotide with a cytosine nucleotide near the beginning of a gene.
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The insertion of a thymine, a guanine, and an adenine nucleotide in that order at the end of a gene.
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Detailed explanation-1: -Which mutation would change the greatest number of amino acids in a protein? The deletion of a single adenine nucleotide in the middle of a gene.
Detailed explanation-2: -Non-conservative mutations can be more severe because they cause a greater change to the protein sequence or expression level. An example would be changing an acidic amino acid into a basic one.
Detailed explanation-3: -A genetic alteration in which a single base pair substitution alters the genetic code in a way that produces an amino acid that is different from the usual amino acid at that position. Some missense variants (or mutations) will alter the function of the protein. Also called missense variant.
Detailed explanation-4: -Substitution Substitution, as related to genomics, is a type of mutation in which one nucleotide is replaced by a different nucleotide. The term can also refer to the replacement of one amino acid in a protein with a different amino acid.