THE MOLECULAR BASIS OF INHERITANCE
DNA MAKES RNA MAKES PROTEIN
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Primase
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DNA polymerase
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TATA box
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Helicase
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Detailed explanation-1: -The TATA box is able to define the direction of transcription and also indicates the DNA strand to be read. Proteins called transcription factors can bind to the TATA box and recruit an enzyme called RNA polymerase, which synthesizes RNA from DNA.
Detailed explanation-2: -The TATA box is essential for transcription and binds either TBP or the Acanthamoeba version of TFIID (32). The start site region is not essential, but serves to constrain the positioning of RNA polymerase II (24).
Detailed explanation-3: -Explanation: The sigma factor is solely required for the initiation of transcription. In fact, the sigma subunit will often fall off of the enzyme during the elongation phase of transcription. Binding of the sigma factor is an important signal for transcription to begin.
Detailed explanation-4: -The TATA-binding protein (TBP) is a general transcription factor that binds specifically to a DNA sequence called the TATA box. This DNA sequence is found about 30 base pairs upstream of the transcription start site in some eukaryotic gene promoters.