THE MOLECULAR BASIS OF INHERITANCE
DNA MAKES RNA MAKES PROTEIN
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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1 and 2
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2 and 3
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1, 2, and 3
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1 and 3
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Detailed explanation-1: -So the correct answer is ‘Either an insertion or a deletion of a base’.
Detailed explanation-2: -Frameshift mutation are caused by the addition or subtraction of nucleotides from the DNA sequence. Because the genetic code is read in triplets, addition or subtraction of 1 or 2 nucleotides causes a shift in the reading frame.
Detailed explanation-3: -A frameshift mutation in a gene refers to the insertion or deletion of nucleotide bases in numbers that are not multiples of three. This is important because a cell reads a gene’s code in groups of three bases when making a protein.
Detailed explanation-4: -Frameshift mutations occur when the coding region of a gene is altered by addition or deletion of a number of base pairs that is not a multiple of three. The occurrence of a deletion versus an insertion type of frameshift depends on the nature of the transient intermediate structure formed during DNA synthesis.