AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

DNA MAKES RNA MAKES PROTEIN

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which statement describes the involvement of this structure in the genetic disease Down syndrome?
A
This gene manufactures a faulty protein that causes all the symptoms of the disorder.
B
This chromosome manufactures a faulty protein that causes all the symptoms of the disorder.
C
There is an extra structure like this one, called a gene, in the cells of a person with Down syndrome that causes all the symptoms of the disorder.
D
There is an extra structure like this one, called a chromosome, in the cells of a person with Down syndrome that causes all the symptoms of the disorder.
Explanation: 

Detailed explanation-1: -Trisomy 21: About 95% of people with Down syndrome have Trisomy 21. With this type of Down syndrome, each cell in the body has 3 separate copies of chromosome 21 instead of the usual 2 copies.

Detailed explanation-2: -Down syndrome is usually caused by an error in cell division called “nondisjunction.” Nondisjunction results in an embryo with three copies of chromosome 21 instead of the usual two. Prior to or at conception, a pair of 21st chromosomes in either the sperm or the egg fails to separate.

Detailed explanation-3: -ZooWeb-Karyotypes, 47, XY, +21. These karyotypes are from abnormal males. There is a full set of 23 homologous pairs of autosomes, and an X and Y, but an extra chromosome 21. These individuals are also said to have Down syndrome.

Detailed explanation-4: -Chromosomal Abnormalities: Trisomy 21 (Down Syndrome)

There is 1 question to complete.