THE MOLECULAR BASIS OF INHERITANCE
DNA MAKES RNA MAKES PROTEIN
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Point mutation (substitution)
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Frameshift mutation
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They have the same effect
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Neither affects the protein
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Detailed explanation-1: -A frameshift variant occurs when there is an addition or loss of nucleotides that shifts the grouping and changes the code for all downstream amino acids. The resulting protein is usually nonfunctional. Insertions, deletions, and duplications can all be frameshift variants.
Detailed explanation-2: -1). Because an insertion or deletion results in a frame-shift that changes the reading of subsequent codons and, therefore, alters the entire amino acid sequence that follows the mutation, insertions and deletions are usually more harmful than a substitution in which only a single amino acid is altered.
Detailed explanation-3: -Answer and Explanation: The type of mutation that is likely to have the greatest effect on a protein is B. Nonsense mutation. This is because a nonsense mutation creates a premature stop codon, leading to an incomplete formation of a protein, severely affecting protein structure and function.