THE MOLECULAR BASIS OF INHERITANCE
DNA MAKES RNA MAKES PROTEIN
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
|
|
Deletion
|
|
|
Insertion
|
|
|
Substitution
|
Detailed explanation-1: -An initiation codon mutation (AUG—-GUG) of the human alpha 1-globin gene. Structural characterization and evidence for a mild thalassemic phenotype.
Detailed explanation-2: -Mutations can be of many types, such as substitution, deletion, insertion, and translocation.
Detailed explanation-3: -Such a substitution could: change a codon to one that encodes a different amino acid and cause a small change in the protein produced. For example, sickle cell anemia is caused by a substitution in the beta-hemoglobin gene, which alters a single amino acid in the protein produced.
Detailed explanation-4: -For example, if codon UAC, which normally codes for the amino acid tyrosine, mutates into UAG, a stop codon, the result is a nonsense mutation.