THE MOLECULAR BASIS OF INHERITANCE
DNA MAKES RNA MAKES PROTEIN
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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adenine
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cytosine
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guanine
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uracil
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Detailed explanation-1: -In DNA, the code letters are A, T, G, and C, which stand for the chemicals adenine, thymine, guanine, and cytosine, respectively. In base pairing, adenine always pairs with thymine, and guanine always pairs with cytosine.
Detailed explanation-2: -Replication relies on complementary base pairing, that is the principle explained by Chargaff’s rules: adenine (A) always bonds with thymine (T) and cytosine (C) always bonds with guanine (G).
Detailed explanation-3: -Under normal circumstances, the nitrogen-containing bases adenine (A) and thymine (T) pair together, and cytosine (C) and guanine (G) pair together. The binding of these base pairs forms the structure of DNA .
Detailed explanation-4: -Guanine and thymine are similarly incompatible. A always pairs with T and G always pairs with C because these are the only combinations that allow for hydrogen bonding to occur, given the spatial constraints of the double helix, which requires there to be one purine and one pyrimidine in each base pair.
Detailed explanation-5: -Erwin Chargaff proposed the Chargaff’s rule. The rule played an essential role in discovering the double-helical structure of DNA. The rule states that in any double-stranded DNA, the ratios between Adenine and Thymine and Guanine and Cytosine are constant and equal.