THE MOLECULAR BASIS OF INHERITANCE
DNA REPLICATION
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Polymerase
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Helicase
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Ligase
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Gyrase
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Detailed explanation-1: -The central enzyme involved is DNA polymerase, which catalyzes the joining of deoxyribonucleoside 5′-triphosphates (dNTPs) to form the growing DNA chain.
Detailed explanation-2: -DNA polymerase and – The main DNA polymerases for nuclear replication. DNA polymerase – It is involved in mitochondrial DNA replication. DNA polymerase – Its main function is to repair DNA.
Detailed explanation-3: -DNA polymerases are responsible for synthesizing DNA: they add nucleotides one by one to the growing DNA chain, incorporating only those that are complementary to the template.
Detailed explanation-4: -DNA polymerases catalyze efficient and high fidelity DNA synthesis. While this reaction favors nucleotide incorporation, polymerases also catalyze a reverse reaction, pyrophosphorolysis, removing the DNA primer terminus and generating deoxynucleoside triphosphates.
Detailed explanation-5: -The primary role of DNA polymerases is to accurately and efficiently replicate the genome in order to ensure the maintenance of the genetic information and its faithful transmission through generations.