AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

DNA REPLICATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Helicase is an enzyme in the nucleus that has which function?
A
It ‘unzips’ the DNA molecule by breaking the bonds between the bases
B
It is responsible for adding new nucleotides to the old strands
C
It closes the DNA molecule
D
It fuses the gaps in the sugar-phosphate backbone
Explanation: 

Detailed explanation-1: -Helicase is a helicase enzyme that plays a crucial role in DNA replication. Helicase unwinds the double-stranded DNA molecule by breaking the hydrogen bonds between nucleotides, making it possible for the two strands to separate.

Detailed explanation-2: -Key enzyme involved in DNA replication, it is responsible for ‘unzipping’ the double helix structure by breaking the hydrogen bonds between bases on opposite strands of the DNA molecule.

Detailed explanation-3: -DNA replication begins when an enzyme called helicase unwinds, and unzips the DNA molecule.

Detailed explanation-4: -The role of the helicases is to utilize the energy derived from nucleoside triphosphate hydrolysis to translocate along nucleic acid strands, unwind/separate the helical structure of double-stranded nucleic acid, and, in some cases, disrupt protein-nucleic acid interactions.

Detailed explanation-5: -Helicases are enzymes involved in the unzipping of the double-stranded DNA molecule at beginning of DNA replication. They do so by binding at DNA sequences called origins on DNA molecule then they break the hydrogen bonds between complementary base pairs causing the two strands of DNA molecule to unzip.

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