THE MOLECULAR BASIS OF INHERITANCE
DNA REPLICATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Semiconservative replication
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Discontinuous replication
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DNA Polymerase
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Single Stranded Binding Proteins
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Detailed explanation-1: -Okazaki fragments are the short lengths of DNA that are produced by the discontinuous replication of the lagging strand. The range of length of these fragments in the bacterial cells is about 1000-2000 nucleotides, while that in eukaryotic cells is approximately 100-200 nucleotides in length.
Detailed explanation-2: -Okazaki fragments are short sequences of DNA nucleotides (approximately 150 to 200 base pairs long in eukaryotes) which are synthesized discontinuously and later linked together by the enzyme DNA ligase to create the lagging strand during DNA replication.
Detailed explanation-3: -On the upper lagging strand, synthesis is discontinuous, since new RNA primers must be added as opening of the replication fork continues to expose new template. This produces a series of disconnected Okazaki fragments.
Detailed explanation-4: -The Process of DNA replication is bidirectional and discontinuous because of the extension of two forks in opposite directions and the appearance of Okazaki fragments on the lagging strand respectively.
Detailed explanation-5: -DNA replication is ‘semi-discontinuous’ because one of the strands is synthesised continuously, while the other strand, discontinuously by the formation of Okazaki fragments.