THE MOLECULAR BASIS OF INHERITANCE
DNA REPLICATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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synthesizes the RNA primer, initiates DNA synthesis and the lagging strand
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repair DNA
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replicate mitochondrial DNA
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synthesizes the leading strand, filling DNA gaps after removal of primer
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Detailed explanation-1: -Either DNA polymerase epsilon or DNA polymerase delta along with DNA ligase can be used to repair UV-damaged DNA. However, it is found that DNA polymerase delta require the presence of both RFC and PCNA in order in DNA repair. In addition, it only produces small amount of fractionated DNA ligated products.
Detailed explanation-2: -In addition to its role in DNA replication, DNA polymerase epsilon fulfils roles in the DNA synthesis step of nucleotide excision and base excision repair, and has been implicated in recombinational processes in the cell.
Detailed explanation-3: -DNA Polymerase Beta It is typically described as a DNA repair enzyme, involved in various types of DNA repair such as Base Excision Repair (BER), Nucleotide Excision Repair (NER), post-replicative Mismatch Repair (MMR), and Double Strand Break Repair (DSBR) Hübscher et al (2002).
Detailed explanation-4: -Most current evidence indicates that DNA polymerases and