AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

DNA REPLICATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Since DNA cannot be fully unwound, many ____ make replication more efficient
A
jigsaws
B
ligases
C
synthesizers
D
origins of replication
Explanation: 

Detailed explanation-1: -The cell cycle will not proceed to the next stage. Due to which the subsequent division will not happen. This will lead to cell death.

Detailed explanation-2: -Therefore, the DNA helix cannot be unwound (Figure 3B), and the replication fork would stall without generation of a double-stranded break in the daughter DNA and unloading of the MCM helicase.

Detailed explanation-3: -DNA unwinding plays a major role in many biological processes, such as replication, transcription, and repair. It can lead to local melting and strand separation and can serve as a key mechanism to promote access to the separate strands of a double-stranded DNA.

Detailed explanation-4: -Because eukaryotic chromosomes are linear and much larger than prokaryotic ones, there are multiple origins of replication in the eukaryotic genome during replication. This means that replication can occur simultaneously in hundreds to thousands of locations along each chromosome.

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