THE MOLECULAR BASIS OF INHERITANCE
DNA REPLICATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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single-strand DNA-binding proteins that stabilizes single-stranded DNA to prevent helicase from opening again in order to maintain the strand separation
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single-strand DNA-binding proteins that destabilizes single-stranded DNA
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catalyses the synthesis of the RNA primer
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extends an Okazaki fragment
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Detailed explanation-1: -During DNA replication, the single-stranded DNA binding protein (SSB) wraps single-stranded DNA (ssDNA) with high affinity to protect it from degradation and prevent secondary structure formation. Although SSB binds ssDNA tightly, it can be repositioned along ssDNA to follow the advancement of the replication fork.
Detailed explanation-2: -SSBs are essential proteins found in all domains of life. SSBs bind ssDNA with high affinity and in a sequence-independent manner and, in doing so, SSBs help to form the central nucleoprotein complex substrate for DNA replication, recombination, and repair processes.
Detailed explanation-3: -Single-Stranded DNA Binding Protein (SSBP) plays a role in DNA replication, recombination, and repair. Due to many cellular processes, like replication and transcription, single-stranded DNA (ssDNA) is exposed. SSBP1 Mechanism. Single-Stranded Binding Proteins stabilize the unwound DNA.
Detailed explanation-4: -DNA Helicases-These proteins bind to the double stranded DNA and stimulate the separation of the two strands. DNA single-stranded binding proteins-These proteins bind to the DNA as a tetramer and stabilize the single-stranded structure that is generated by the action of the helicases.