AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

DNA REPLICATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The enzyme DNA ligase is required continuously during DNA replication because
A
fragments of the leading strand must be joined together.
B
fragments of the lagging strand must be joined together
C
3´-deoxynucleoside triphosphates must be converted to 5´-deoxynucleoside triphosphates.
D
the complex of proteins that work together at the replication fork must be prevented from falling apart
Explanation: 

Detailed explanation-1: -DNA ligase binds the Okazaki fragments together. In the four stage of DNA replication, the enzyme DNA ligase binds the Okazaki fragments together to make a continuous daughter strand. This creates a completely new DNA strand for each parent DNA strand.

Detailed explanation-2: -Okazaki fragments are small sections of DNA that are formed during discontinuous synthesis of the lagging strand during DNA replication. They are important because they allow for both daughter strands to be synthesized, which are necessary for cell division.

Detailed explanation-3: -Figure 3: Replication of the leading DNA strand is continuous, while replication along the lagging strand is discontinuous. After a short length of the DNA has been unwound, synthesis must proceed in the 5’ to 3’ direction; that is, in the direction opposite that of the unwinding.

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