AP BIOLOGY

Detailed explanation-1: -Human telomeres, for example, range in size from 2-50 kilobases and consist of approximately 300-8, 000 precise repeats of the sequence CCCTAA/TTAGGG.

Detailed explanation-2: -A highly conserved repetitive DNA sequence, (TTAGGG)n, has been isolated from a human recombinant repetitive DNA library. Quantitative hybridization to chromosomes sorted by flow cytometry indicates that comparable amounts of this sequence are present on each human chromosome.

Detailed explanation-3: -Telomeres are repetitive DNA sequences found at the end of linear chromosomes. In mammals these are made up of tandem repeats of the nucleotide sequence TTAGGG and are bound to the protein complex shelterin. Some human cells contain as many as 1, 500 to 2, 000 repeats of this sequence at the ends of each chromosome.

Detailed explanation-4: -Telomeres are repetitive DNA sequences that are wrapped in specific protein complexes and located at the ends of linear chromosomes. Telomeres distinguish natural chromosome ends from DNA double-stranded breaks and thus promote genome stability.

Detailed explanation-5: -The ends of eukaryotic chromosomes contain repetitive DNA sequences called telomeres, which help to ensure that no information is lost from chromosome ends during DNA replication.