AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

DNA REPLICATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The short primer sequence is synthesised by ..
A
Helicase
B
Topoisomerase
C
DNA polymerase
D
Primase
Explanation: 

Detailed explanation-1: -Primase is an enzyme that synthesizes short RNA sequences called primers. These primers serve as a starting point for DNA synthesis. Since primase produces RNA molecules, the enzyme is a type of RNA polymerase.

Detailed explanation-2: -A primer must be synthesized by an enzyme called primase, which is a type of RNA polymerase, before DNA replication can occur. The synthesis of a primer is necessary because the enzymes that synthesize DNA, which are called DNA polymerases, can only attach new DNA nucleotides to an existing strand of nucleotides.

Detailed explanation-3: -Primases typically synthesize primers from ribonucleotides (NTPs); however, primases with polymerase capabilities also have an affinity for deoxyribonucleotides (dNTPs).

Detailed explanation-4: -In contrast to DNA synthesis, the synthesis of RNA can initiate de novo, and an enzyme called primase synthesizes short fragments of RNA (e.g., three to ten nucleotides long) complementary to the lagging strand template at the replication fork.

Detailed explanation-5: -Primase Definition DNA is used as a template to create messenger RNA, which will be transported to the cytoplasm to synthesize proteins with the help of other RNA structures.

There is 1 question to complete.