THE MOLECULAR BASIS OF INHERITANCE
DNA REPLICATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Topoisomerase
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DNA Helicase
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DNA Polymerase
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Exonuclease
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Detailed explanation-1: -DNA helicase is the enzyme responsible for separating or unwinding two complementary strands of DNA by breaking the hydrogen bonds between them, creating the replication fork in preparation for DNA replication.
Detailed explanation-2: -DNA helicases are molecular motors. Through conformational changes caused by ATP hydrolysis and binding, they move along the template double helix, break the hydrogen bonds between the two strands and separate the template chains, so that the genetic information can be accessed.
Detailed explanation-3: -Then, a protein known as helicase attaches to and breaks apart the hydrogen bonds between the bases on the DNA strands, thereby pulling apart the two strands.
Detailed explanation-4: -DNA helicase is an enzyme that unwinds the DNA double helix by breaking the hydrogen bonds between the complementary bases.