AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

DNA REPLICATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What did Meselson & Stahl discover?
A
A=T, C=G
B
bacterial transformation
C
DNA is semi-conservatively replicated
D
RNA primers
Explanation: 

Detailed explanation-1: -The experiment done by Meselson and Stahl demonstrated that DNA replicated semi-conservatively, meaning that each strand in a DNA molecule serves as a template for synthesis of a new, complementary strand.

Detailed explanation-2: -Meselson & Stahl reasoned that these experiments showed that DNA replication was semi-conservative: the DNA strands separate and each makes a copy of itself, so that each daughter molecule comprises one “old” and one “new” strand.

Detailed explanation-3: -In an experiment later named for them, Matthew Stanley Meselson and Franklin William Stahl in the US demonstrated during the 1950s the semi-conservative replication of DNA, such that each daughter DNA molecule contains one new daughter subunit and one subunit conserved from the parental DNA molecule.

Detailed explanation-4: -Meselson and Stahl Experiment was an experimental proof for semiconservative DNA replication. In 1958, Matthew Meselson and Franklin Stahl conducted an experiment on E. coli which divides in 20 minutes, to study the replication of DNA.

Detailed explanation-5: -That left the scientists with only two options: either DNA replicated semiconservatively, as Watson and Crick had predicted, or it replicated dispersively. To differentiate between the two, Meselson and Stahl had to let the cells divide again and then sample the DNA after a second round of replication.

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