AP BIOLOGY

Detailed explanation-1: -Special proteins are responsible for loading primase at the origin of replication so that leading strand DNA synthesis can commence. In a subsequent step, other replication proteins cause primase to initiate DNA replication on the opposite lagging strand.

Detailed explanation-2: -DNA primases are enzymes whose continual activity is required at the DNA replication fork. They catalyze the synthesis of short RNA molecules used as primers for DNA polymerases. Primers are synthesized from ribonucleoside triphosphates and are four to fifteen nucleotides long.

Detailed explanation-3: -Primase functions by synthesizing short RNA sequences that are complementary to a single-stranded piece of DNA, which serves as its template. It is critical that primers are synthesized by primase before DNA replication can occur.

Detailed explanation-4: -A short piece of RNA? called a primer? (produced by an enzyme called primase) comes along and binds to the end of the leading strand. The primer acts as the starting point for DNA synthesis.