THE MOLECULAR BASIS OF INHERITANCE
DNA REPLICATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Leading strand is replicated in one continuous piece, lagging strand is replicated in chunks
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Leading strand is replicated in chunks, lagging strand is replicated in one continous piece
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Leading strand gets replicated 5’ to 3’, lagging strand gets replicated 3’ to 5’
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Leading strand has Okasaki Fragments and the lagging strand does not
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Detailed explanation-1: -The major difference between a lagging and leading strand is that the lagging strand replicates discontinuously forming short fragments, whereas the leading strand replicates continuously.
Detailed explanation-2: -The lagging strand is synthesized continuously, whereas the leading strand is synthesized in short fragments that are ultimately stitched together. The leading strand is synthesized at twice the rate of the lagging strand. one RNA primer attaches to the 5’ end of the parent strand and the other primer to the 3’ end.
Detailed explanation-3: -Therein lies the main difference between the two: A leading indicator looks forward at future outcomes and events. A lagging indicator looks back at whether the intended result was achieved.
Detailed explanation-4: -On the leading strand, DNA synthesis occurs continuously. On the lagging strand, DNA synthesis restarts many times as the helix unwinds, resulting in many short fragments called “Okazaki fragments.” DNA ligase joins the Okazaki fragments together into a single DNA molecule.
Detailed explanation-5: -Okazaki fragments are relatively short strands. They are the end products or the newly synthesized DNA fragments that are formed on the lagging strand. A lagging strand is defined as the DNA strand that is replicated discontinuously from the five-foot to three-foot direction.