THE MOLECULAR BASIS OF INHERITANCE
DNA REPLICATION
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
|
|
Nucleotide
|
|
|
Nucleosome
|
|
|
DNA-Histone Complex
|
|
|
Secondary Structure of DNA
|
Detailed explanation-1: -The nucleosome is composed of an octameric core of histone proteins around which the DNA double helix is wrapped.
Detailed explanation-2: -DNA molecules first wrap around the histone proteins forming beads on string structure called nucleosomes. Nucleosomes further [inaudible] and condense/gather to form fibrous material which is called chromatin.
Detailed explanation-3: -The nucleosome is the fundamental subunit of chromatin. Each nucleosome is composed of a little less than two turns of DNA wrapped around a set of eight proteins called histones, which are known as a histone octamer. Each histone octamer is composed of two copies each of the histone proteins H2A, H2B, H3, and H4.
Detailed explanation-4: -Each nucleosome is made up of 1.65 loops of DNA wrapped around 8 histone proteins. A nucleosome’s wrapped DNA molecule contains approximately 146 base pairs. The nucleosome contains two copies of each of the four nucleosome histones – H2A, H2B, H4 and H3. Histone octamers are the collective name for the eight histones.
Detailed explanation-5: -The DNA of eukaryotic cells is tightly bound to small basic proteins (histones) that package the DNA in an orderly way in the cell nucleus.