THE MOLECULAR BASIS OF INHERITANCE
DNA REPLICATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Binding proteins
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Fragmenting lagging strand
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Okazaki segments
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Coding strands
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Detailed explanation-1: -So, the correct option is ‘DNA ligase ’.
Detailed explanation-2: -What are Okazaki Fragments For? Okazaki fragments are short sections of DNA formed at the time of discontinuous synthesis of the lagging strand during replication of DNA. It is essential as it allows for the synthesis of both the daughter strands required for cell division.
Detailed explanation-3: -The lagging strand is a single DNA strand that, during DNA replication, is replicated in the 5′ – 3′ direction (opposite direction to the replication fork). DNA is added to the lagging strand in discontinuous chunks called ‘okazaki fragments’.
Detailed explanation-4: -Newly synthesized DNA, otherwise known as Okazaki fragments, are bound by DNA ligase, which forms a new strand of DNA. There are two strands that are created when DNA is synthesized.
Detailed explanation-5: -Word origin: named after its discoverers, Reiji Okazaki and his wife, Tsuneko Okazaki, while studying replication of bacteriophage DNA in Escherichia coli in 1968.