AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

DNA REPLICATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What prevents the DNA repair system from “repairing” telomeres?
A
Telomerase is bound to telomeres, and thus blocks the repair system from binding to telomeres.
B
Telomerase catalyzes reactions that interfere with the repair system.
C
DNA polymerase blocks the repair system from accessing the telomere DNA.
D
Protective proteins bind to telomeres, and therefore the repair system does not recognize telomeres as breaks
Explanation: 

Detailed explanation-1: -Telomeres are at the end of the chromosome, and DNA is replicated in only one direction. E. Protective proteins bind to telomeres, and therefore the repair system does not recognize telomeres as breaks.

Detailed explanation-2: -Telomerase counteracts telomere shortening An enzyme named telomerase adds bases to the ends of telomeres. In young cells, telomerase keeps telomeres from wearing down too much. But as cells divide repeatedly, there is not enough telomerase, so the telomeres grow shorter and the cells age.

Detailed explanation-3: -As DNA polymerase alone cannot replicate the ends of chromosomes, telomerase aids in their replication and prevents chromosome degradation.

Detailed explanation-4: -Telomerase counteracts the shortening of telomeres by adding small repeated segments of DNA to the ends of chromosomes each time the cell divides. In most types of cells, telomerase is either undetectable or active at very low levels.

There is 1 question to complete.