THE MOLECULAR BASIS OF INHERITANCE
DNA REPLICATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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At one end
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At both ends
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At the origin
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In the exact middle of the molecule
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Detailed explanation-1: -DNA replication initiates at specific points, called origins, where the DNA double helix is unwound. A short segment of RNA, called a primer, is then synthesized and acts as a starting point for new DNA synthesis. An enzyme called DNA polymerase next begins replicating the DNA by matching bases to the original strand.
Detailed explanation-2: -During initiation, the replication machineries–termed replisomes–are assembled on DNA in a bidirectional fashion. These assembly loci constitute the start sites of DNA replication or replication origins.
Detailed explanation-3: -Eukaryotes initiate DNA replication at multiple points in the chromosome, so replication forks meet and terminate at many points in the chromosome. Because eukaryotes have linear chromosomes, DNA replication is unable to reach the very end of the chromosomes.