THE MOLECULAR BASIS OF INHERITANCE
DNA REPLICATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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DNA polymerase I
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DNA polymerase III
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Detailed explanation-1: -For example, DNA polymerase III does most of the elongation work, adding nucleotides one by one to the 3’ end of the new and growing single strand.
Detailed explanation-2: -The main function of the third polymerase, Pol III, is duplication of the chromosomal DNA, while other DNA polymerases are involved mostly in DNA repair and translesion DNA synthesis. Together with a DNA helicase and a primase, Pol III HE participates in the replicative apparatus that acts at the replication fork.
Detailed explanation-3: -DNA polymerases can only add nucleotides to the 3’ end of an existing DNA strand. (They use the free-OH group found at the 3’ end as a “hook, ” adding a nucleotide to this group in the polymerization reaction.)