THE MOLECULAR BASIS OF INHERITANCE
DNA REPLICATION
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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DNA Ligase
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DNA polymerase I
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DNA polymerase III
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DNA Helicase
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Detailed explanation-1: -Because of its 5′ to 3′ exonuclease activity, DNA polymerase I removes RNA primers and fills the gaps between Okazaki fragments with DNA.
Detailed explanation-2: -Once both the continuous and discontinuous strands are formed, an enzyme called exonuclease removes all RNA primers from the original strands. These primers are then replaced with appropriate bases. Another exonuclease “proofreads” the newly formed DNA to check, remove and replace any errors.
Detailed explanation-3: -DNA polymerase I (pol I) processes RNA primers during lagging-strand synthesis and fills small gaps during DNA repair reactions.
Detailed explanation-4: -In bacteria, all three DNA polymerases (I, II and III) have the ability to proofread, using 3’