THE MOLECULAR BASIS OF INHERITANCE
DNA REPLICATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Antiparallel nature of DNA
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End specificity of polymerase
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SSB protein
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Helicase
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Detailed explanation-1: -SSB protein binds to the single stranded DNA during replication to stabilize it but does not take any part in new strand synthesis.
Detailed explanation-2: -Which of the following proteins is not necessary during DNA replication? Explanation: RNA polymerase is an enzyme that transcribes RNA from DNA; it is not essential for DNA replication.
Detailed explanation-3: -Proteins bound on DNA also provide significant obstacles for DNA replication, as replication fork proteins can collide with them and become displaced from DNA. These include various DNA binding proteins such as the transcription machinery. Another physical barrier could be the DNA structure itself.
Detailed explanation-4: -Most organisms, including mammals, use bi-directional replication. There are four basic components required to initiate and propagate DNA synthesis. They are: substrates, template, primer and enzymes.
Detailed explanation-5: -DNA replication requires other enzymes in addition to DNA polymerase, including DNA primase, DNA helicase, DNA ligase, and topoisomerase.