AP BIOLOGY

Detailed explanation-1: -Okazaki fragments are short sequences of DNA nucleotides (approximately 150 to 200 base pairs long in eukaryotes) which are synthesized discontinuously and later linked together by the enzyme DNA ligase to create the lagging strand during DNA replication.

Detailed explanation-2: -DNA Ligase is the enzyme which helps in joining the fragments of DNA, basically, it acts as a glue.

Detailed explanation-3: -DNA ligase is responsible for joining Okazaki fragments on the lagging strand during replication.

Detailed explanation-4: -The strand with the Okazaki fragments is known as the lagging strand. As synthesis proceeds, an enzyme removes the RNA primer, which is then replaced with DNA nucleotides, and the gaps between fragments are sealed by an enzyme called DNA ligase.