AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

DNA REPLICATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following is the first step in DNA replication?
A
Helicase breaks the hydrogen bonds between the bases to split the original strand.
B
Primase marks where to start building the new strand of DNA
C
DNA Polymerase starts to attach new nucleotides to the original strand
D
There are fragments left on the lagging strand when DNA polymerase is done
E
Ligase glues together the fragments on the lagging strand of DNA
Explanation: 

Detailed explanation-1: -The first step in DNA replication is to ‘unzip’ the double helix structure of the DNA? molecule. This is carried out by an enzyme? called helicase which breaks the hydrogen bonds? holding the complementary? bases? of DNA together (A with T, C with G).

Detailed explanation-2: -What step occurs after DNA helicase breaks hydrogen bonds to separate DNA strands? DNA polymerase adds nucleotides to the leading strand continuously and to the lagging strand discontinuously in fragments.

Detailed explanation-3: -DNA replication is the process whereby a molecule of DNA is copied to form two identical molecules. First, an enzyme called a DNA helicase separates the two strands of the DNA double helix. This forms a structure called a replication fork that has two exposed single strands.

Detailed explanation-4: -The first step in DNA replication is the unzipping of DNA by the enzyme helicase. This opens up the DNA nucleotides so that they can be read and a complementary strand can be formed.

Detailed explanation-5: -Key enzyme involved in DNA replication, it is responsible for ‘unzipping’ the double helix structure by breaking the hydrogen bonds between bases on opposite strands of the DNA molecule.

There is 1 question to complete.