AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

DNA REPLICATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following is the third step in DNA replication?
A
Helicase breaks the hydrogen bonds between the bases to split the original strand.
B
Primase marks where to start building the new strand of DNA
C
DNA Polymerase starts to attach new nucleotides to the original strand
D
There are fragments left on the lagging strand when DNA polymerase is done
E
Ligase glues together the fragments on the lagging strand of DNA
Explanation: 

Detailed explanation-1: -Elongation. Finally, elongation–the addition of nucleotides to the new DNA strand–begins after the primer has been added. Synthesis of the growing strand involves adding nucleotides, one by one, in the exact order specified by the original (template) strand.

Detailed explanation-2: -Replication occurs in three major steps: the opening of the double helix and separation of the DNA strands, the priming of the template strand, and the assembly of the new DNA segment.

Detailed explanation-3: -Step 3: Elongation Enzymes known as DNA polymerases are responsible creating the new strand by a process called elongation. There are five different known types of DNA polymerases in bacteria and human cells.

Detailed explanation-4: -Which of the following is created to provide a free 3’ hydroxyl group, enabling the initiation of DNA replication? Explanation: RNA primer is the correct answer. A protein called RNA primase reads the existing DNA strand and adds a short sequence of RNA nucleotides.

Detailed explanation-5: -DNA polymerases can only add nucleotides to the 3’ end of an existing DNA strand. (They use the free-OH group found at the 3’ end as a “hook, ” adding a nucleotide to this group in the polymerization reaction.)

There is 1 question to complete.