THE MOLECULAR BASIS OF INHERITANCE
DNA REPLICATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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It can synthesize DNA in the 5’ to 3’ direction
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It can synthesize DNA in the 3’ to 5’ direction
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It can synthesize mRNA in the 3’ to 5’ direction
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It can synthesize mRNA in the 5’ to 3’ direction
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Detailed explanation-1: -Answer and Explanation: The answer to the question would be, option b. It can synthesize DNA in 5’ to 3’ direction.
Detailed explanation-2: -DNA polymerases can only make DNA in the 5’ to 3’ direction, and this poses a problem during replication. A DNA double helix is always anti-parallel; in other words, one strand runs in the 5’ to 3’ direction, while the other runs in the 3’ to 5’ direction.
Detailed explanation-3: -The need for accuracy probably explains why DNA replication occurs only in the 5′-to-3′ direction. If there were a DNA polymerase that added deoxyribonucleoside triphosphates in the 3′-to-5′ direction, the growing 5′-chain end, rather than the incoming mononucleotide, would carry the activating triphosphate.