THE MOLECULAR BASIS OF INHERITANCE
DNA REPLICATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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DNA polymerase binds to the leading strand
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DNA is unwound
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Hydrogen bonds form between bases
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chromosomes condense
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Detailed explanation-1: -The initiation of DNA replication occurs in two steps. First, a so-called initiator protein unwinds a short stretch of the DNA double helix. Then, a protein known as helicase attaches to and breaks apart the hydrogen bonds between the bases on the DNA strands, thereby pulling apart the two strands.
Detailed explanation-2: -DNA replication occurs in the nucleus in eukaryotic cells and in the nucleoid region in prokaryotic cells. DNA replication occurs in S phase during the cell cycle prior to cell division.
Detailed explanation-3: -Therefore, it is not surprising that the initiation of DNA replication is a highly regulated process. It begins when initiator proteins bind in multiple copies to specific sites in the replication origin, wrapping the DNA around the proteins to form a large protein–DNA complex.