THE MOLECULAR BASIS OF INHERITANCE
DNA REPLICATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Helicase breaks the hydrogen bonds
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Topoisomerase uncoils the DNA
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DNA polymerase adds new nucleotides
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Ligase seals the DNA fragments together
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Detailed explanation-1: -DNA helicases are molecular motors. Through conformational changes caused by ATP hydrolysis and binding, they move along the template double helix, break the hydrogen bonds between the two strands and separate the template chains, so that the genetic information can be accessed.
Detailed explanation-2: -Posted April 29, 2022. Hydrogen bonds in DNA replication are broken down by the helicase class of enzymes. This causes the double-stranded DNA molecule to unzip into two single strands, allowing each strand to be replicated.
Detailed explanation-3: -Key enzyme involved in DNA replication, it is responsible for ‘unzipping’ the double helix structure by breaking the hydrogen bonds between bases on opposite strands of the DNA molecule.
Detailed explanation-4: -DNA helicase continues to unwind the DNA forming a structure called the replication fork, which is named for the forked appearance of the two strands of DNA as they are unzipped apart. The process of breaking the hydrogen bonds between the nucleotide base pairs in double-stranded DNA requires energy.