THE MOLECULAR BASIS OF INHERITANCE
DNA REPLICATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Primase adds primers
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Topoisomerase uncoils the DNA
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DNA polymerase adds new nucletides
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Ligase seals the DNA fragments together
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Detailed explanation-1: -Primase synthesizes RNA primers complementary to the DNA strand. DNA polymerase III extends the primers, adding on to the 3’ end, to make the bulk of the new DNA. RNA primers are removed and replaced with DNA by DNA polymerase I. The gaps between DNA fragments are sealed by DNA ligase.
Detailed explanation-2: -Replication occurs in three major steps: the opening of the double helix and separation of the DNA strands, the priming of the template strand, and the assembly of the new DNA segment.
Detailed explanation-3: -Because DNA polymerases extend primers only in the 5′ to 3′ direction, they are unable to copy the extreme 5′ ends of linear DNA molecules.
Detailed explanation-4: -DNA polymerase adds nucleotides to the 3’ end of a primer, extending the new chain in a 5’