AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

DNA REPLICATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of these occurs first?
A
Helicase breaks the hydrogen bonds
B
The DNA uncoils
C
DNA polymerase adds new nucleotides
D
Primase adds primers
Explanation: 

Detailed explanation-1: -First, a so-called initiator protein unwinds a short stretch of the DNA double helix. Then, a protein known as helicase attaches to and breaks apart the hydrogen bonds between the bases on the DNA strands, thereby pulling apart the two strands.

Detailed explanation-2: -Synthases are a class of enzyme that act as catalysts for joining two molecules. Helicase uncoils double-stranded DNA, allowing the formation of the replication fork.

Detailed explanation-3: -In general, DNA is replicated by uncoiling of the helix, strand separation by breaking of the hydrogen bonds between the complementary strands, and synthesis of two new strands by complementary base pairing. Replication begins at a specific site in the DNA called the origin of replication.

Detailed explanation-4: -During DNA replication, DNA helicases unwind DNA at positions called origins where synthesis will be initiated. DNA helicase continues to unwind the DNA forming a structure called the replication fork, which is named for the forked appearance of the two strands of DNA as they are unzipped apart.

There is 1 question to complete.