THE MOLECULAR BASIS OF INHERITANCE
DNA REPLICATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Which statement about Okazaki fragments is true?
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They occur because DNA polymerase operates in only one direction along a strand of DNA.
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They act as a primer that initiates DNA replication.
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If they did not exist, the ends of chromosomes would get shorter with every replication.
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They reduce the mutation rate during DNA replication.
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Explanation:
Detailed explanation-1: -Which of the following is true regarding Okazaki fragment? Okazaki fragments are segments of DNA attached to an RNA initiator component. They are related to the lagging strand. Helicase acts on the lagging strand to unwind dsDNA.
Detailed explanation-2: -These fragments are formed on the lagging strand for the synthesis of DNA. The direction is 5’ to 3’ toward the replication fork. These fragments make the replication of only one of the two strands possible hence increasing the efficiency of replication.
Detailed explanation-3: -During lagging strand synthesis, DNA ligase I connects the Okazaki fragments, following replacement of the RNA primers with DNA nucleotides by DNA polymerase
There is 1 question to complete.