AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

GENE MUTATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
A base pair substitution can result in all of the following except ____
A
Missense mutation
B
Frameshift Mutation
C
Silent Mutation
D
Nonsense mutation
Explanation: 

Detailed explanation-1: -C is correct. Insertion or deletion of three (or multiples of 3) nucleotides does not result in a frameshift mutation.

Detailed explanation-2: -Insertions and deletions cause frameshift mutations, while the exchange of one base from another (substitution) causes base substitution mutations. So, this is the key difference between frameshift mutation and base substitution mutation.

Detailed explanation-3: -Substitution mutations can be good, bad, or have no effect. They cause three specific types of point mutation: silent, missense, and nonsense mutations.

Detailed explanation-4: -So the correct answer is ‘Either an insertion or a deletion of a base’.

There is 1 question to complete.