AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

GENE MUTATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
A DNA strand that originally reads 5’-GATATC-3’ undergoes a mutation that changes it to 5’-GATCATC-3’. This is an example of what type of mutation?
A
Insertion
B
Point mutation
C
Nonsense mutation
D
Deletion
Explanation: 

Detailed explanation-1: -QUESTION. A DNA strand that originally reads 5’-GATATC-3’ undergoes a mutation that changes it to 5’-GATCATC-3’. This is an example of what type of mutation? Insertion is a type of mutation where there is an extra nucleotide bases added or inserted on the chain.

Detailed explanation-2: -So the correct answer is “Palindromic sequence".

Detailed explanation-3: -Such a substitution could: change a codon to one that encodes a different amino acid and cause a small change in the protein produced. For example, sickle cell anemia is caused by a substitution in the beta-hemoglobin gene, which alters a single amino acid in the protein produced.

Detailed explanation-4: -It is a type of frameshift mutation characterized by the loss of one or more nucleotides from the segment of DNA. Example of deletion mutation is DiGeorge syndrome. DiGeorge syndrome is a disorder caused due to the deletion of a small segment of chromosome 22.

Detailed explanation-5: -Insertion Mutation Examples For example, some diseases caused by insertional mutations include: Fragile X Syndrome. Huntington’s Disease. Myotonic dystrophy.

There is 1 question to complete.