AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

GENE MUTATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
a mutation in which one or more pairs of nucleotides are removed from a gene
A
silent mutation
B
insertion mutation
C
deletion mutation
D
missense mutation
Explanation: 

Detailed explanation-1: -A deletion changes the DNA sequence by removing at least one nucleotide in a gene. Small deletions remove one or a few nucleotides within a gene, while larger deletions can remove an entire gene or several neighboring genes. The deleted DNA may alter the function of the affected protein or proteins.

Detailed explanation-2: -Frameshift mutations Insertion or deletion of one or more nucleotides during replication can also lead to another type of mutation known as a frameshift mutation. The outcome of a frameshift mutation is complete alteration of the amino acid sequence of a protein.

Detailed explanation-3: -Definition. A deletion, as related to genomics, is a type of mutation that involves the loss of one or more nucleotides from a segment of DNA. A deletion can involve the loss of any number of nucleotides, from a single nucleotide to an entire piece of a chromosome.

Detailed explanation-4: -Mutations can be of many types, such as substitution, deletion, insertion, and translocation.

Detailed explanation-5: -In the case of deletion mutations, one nucleobase is removed from the DNA sequence usually during DNA replication. Frameshift: this type of mutation occurs as a result of deletion point mutations.

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