AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

GENE MUTATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Adding or deleting DNA bases and causing the reading frame to shift is called ____ Look at this example:THE CAT HATTTH ECA THA T
A
Inversion
B
Translocation
C
Substitution
D
Frameshift mutation
Explanation: 

Detailed explanation-1: -Crohn’s disease, cystic fibrosis, and certain types of cancer are due to frameshift mutations.

Detailed explanation-2: -An insertion or deletion involving a number of base pairs that is not a multiple of three, which consequently disrupts the triplet reading frame of a DNA sequence.

Detailed explanation-3: -Point Mutation: Sickle cell anemia is caused by point mutations. Frameshift Mutation: Tay-Sachs disease is caused by frameshift mutations.

Detailed explanation-4: -Deletion mutations remove one or more DNA bases. Unless they happen in multiples of 3 bases, insertions and deletions shift the reading frame-which is why they’re also called frameshift mutations. A frameshift changes the grouping of bases into codons, affecting all the amino acids downstream of the mutation.

There is 1 question to complete.