AP BIOLOGY

Detailed explanation-1: -The transformation of a normal cell into a cancer cell takes place through a sequence of a small number of discrete genetic events, somatic mutations: thus, cancer can be regarded properly as a genetic disease of somatic cells.

Detailed explanation-2: -Cancer tumors are a unique class of somatic mutations. The tumor arises when a gene involved in cell division, a protooncogene, is mutated. All of the daughter cells contain this mutation.

Detailed explanation-3: -Cancers are caused by damage to the DNA in your cells. These changes are called “gene mutations.” Gene mutations can build up in cells in your body over time. Cells with too many mutations may stop working normally, grow out of control and become cancerous.

Detailed explanation-4: -Common somatic mutation conditions include: Skin cancer. Lung cancer. McCune-Albright syndrome.

Detailed explanation-5: -Clinical example: Cancer Most cancers are a result of somatic mutations, which is why many cancers are localised to a particular organ or tissue of the body.