THE MOLECULAR BASIS OF INHERITANCE
GENE MUTATION
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Detailed explanation-1: -Insertions, deletions, and duplications can all be frameshift variants. Some regions of DNA contain short sequences of nucleotides that are repeated a number of times in a row.
Detailed explanation-2: -A frameshift mutation is a genetic mutation caused by a deletion or insertion in a DNA sequence that shifts the way the sequence is read. A DNA sequence is a chain of many smaller molecules called nucleotides.
Detailed explanation-3: -An insertion or deletion involving a number of base pairs that is not a multiple of three, which consequently disrupts the triplet reading frame of a DNA sequence.
Detailed explanation-4: -Insertion or deletion of three (or multiples of 3) nucleotides does not result in a frameshift mutation. It only results in the presence (or absence) of some amino acids in the polypeptide.