THE MOLECULAR BASIS OF INHERITANCE
GENE MUTATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Addition of one or more nucleic acids
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Removal of one or more nucleic acids
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Replacement of one or more nucleic acids
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When codons shift ____ nucleic acids are separated from their original marriage
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Copying or doubling of a sequence
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Detailed explanation-1: -Listen to pronunciation. (FRAYM-shift myoo-TAY-shun) An insertion or deletion involving a number of base pairs that is not a multiple of three, which consequently disrupts the triplet reading frame of a DNA sequence.
Detailed explanation-2: -Frameshift Mutation If a mutation disrupts this normal reading frame, then the entire gene sequence following the mutation will be incorrectly read. This can result in the addition of the wrong amino acids to the protein and/or the creation of a codon that stops the protein from growing longer.
Detailed explanation-3: -A frameshift variant occurs when there is an addition or loss of nucleotides that shifts the grouping and changes the code for all downstream amino acids. The resulting protein is usually nonfunctional.
Detailed explanation-4: -Frameshift mutations are deletions or additions of 1, 2, or 4 nucleotides that change the ribosome reading frame and cause premature termination of translation at a new nonsense or chain termination codon (TAA, TAG, and TGA).