AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

GENE MUTATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
How do you know when to STOP translating a strand of mRNA?
A
look for STOP on the decoder
B
stop at the end of the strand
C
you don’t
D
when Ms. H tells me to
Explanation: 

Detailed explanation-1: -Translation ends in a process called termination. Termination happens when a stop codon in the mRNA (UAA, UAG, or UGA) enters the A site. Stop codons are recognized by proteins called release factors, which fit neatly into the P site (though they aren’t tRNAs).

Detailed explanation-2: -The presence of a stop codon-UAA, UAG or UGA-in the A site of the ribosome is generally a signal to terminate protein synthesis. This process constitutes the last essential stage of translation, as it ensures the formation of full-sized proteins.

Detailed explanation-3: -Stop Codons Mark the End of Translation The end of the protein-coding message is signaled by the presence of one of three codons (UAA, UAG, or UGA) called stop codons (see Figure 6-50). These are not recognized by a tRNA and do not specify an amino acid, but instead signal to the ribosome to stop translation.

Detailed explanation-4: -It was found that the miRNA–RISC complex associated with an anti-translation initiation factor, eIF6, which inhibits joining of the 60S to the 40S subunits, thus preventing translation initiation (Chendrimada et al, 2007).

Detailed explanation-5: -Transcription termination RNA polymerase will keep transcribing until it gets signals to stop. The process of ending transcription is called termination, and it happens once the polymerase transcribes a sequence of DNA known as a terminator.

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