THE MOLECULAR BASIS OF INHERITANCE
GENE MUTATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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If below is the wild-type DNA sequence, which one shows a point mutation?5’-ATTCGC-3’
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5’-AATTCGC-3’
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5’-ATCCGC-3’
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5’-ATCGC-3’
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5’-ATTCGC-3’
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Explanation:
Detailed explanation-1: -There are two types of point mutations: transition mutations and transversion mutations. Transition mutations occur when a pyrimidine base (i.e., thymine [T] or cytosine [C]) substitutes for another pyrimidine base or when a purine base (i.e., adenine [A] or guanine [G]) substitutes for another purine base.
Detailed explanation-2: -Types of Point Mutations. We are going to focus on the following point mutations: frameshift, silent, nonsense, and missense. Let’s start with a frameshift mutation, where there’s an insertion or deletion of one or more bases.
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